群馬大学生体調節研究所 遺伝生化学分野 泉研究室

When I was a master course student, I studied protein biochemistry using proteomics technic at Tokyo Metropolitan University. I received Ph.D. in Department of Cellular Genetics of the National Institute of Genetics (NIG) under the supervision of Dr. Tamotsu Yoshimori. The research theme of doctor course was the molecular mechanism of autophagosome formation (one of the membrane traffic). In October 2010, I was appointed as an assistant professor of Dr. Izumi’s lab in Institute for Molecular and Cellular Regulation, Gunma University, where I have started research of "regulated exocytosis". In particular, I am interested in molecular mechanism and membrane dynamics of insulin granule exocytosis from pancreatic beta cells.

1. Tabata K, Matsunaga K, Sakane A, Sasaki T, Noda T, Yoshimori T (2010). Rubicon and PLEKHM1 negatively regulate the endocytic/autophagic pathway via a novel Rab7-binding domain. Mol. Biol. Cell, 21, 4162-4172.
2. Matsunaga K, Morita E, Saitoh T, Akira S, Ktistakis NT, Izumi T, Noda T, Yoshimori T (2010). Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L. J. Cell Biol., 190, 511-521.
3. Taguchi-Atarashi N, Hamasaki M, Matsunaga K, Omori H, Ktistakis NT, Yoshimori T, Noda T (2010). Modulation of local Ptdlns3P levels by the PI phosphatase MTMR3 regulates constitutive autophagy. Traffic, 11, 468-478.
4. Saitoh T, Fujita N, Hayashi T, Takahara K, Satoh T, Lee H, Matsunaga K, Kageyama S, Omori H, Noda T, Yamamoto N, Kawai T, Ishii K, Takeuchi O, Yoshimori T, Akira S (2009). Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response. Proc. Natl. Acad. Sci. U. S. A., 106, 20842-20846.
5. Matsunaga K, Saitoh T, Tabata K, Omori H, Satoh T, Kurotori N, Maejima I, Shirahama-Noda K, Ichimura T, Isobe T, Akira S, Noda T, Yoshimori T (2009). Two Beclin-1 binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages. Nat. Cell Biol., 11, 385-396